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Lymphoma is a cancer of a part of the immune system called the lymph system. The lymphatic system is a network of blood vessel-like tubes connecting many small glands called lymph nodes. This system contains large numbers of specialized white blood cells, called lymphocytes, which fight infection. Sometimes lymphocytes become abnormal and reproduce, making more abnormal cells.

There are two major kinds of lymphoma. Hodgkin disease is considered one of the most curable forms of cancer, especially if it is diagnosed and treated early. The prognosis for Non-Hodgkin lymphoma can be good but is linked to the type of lymphoma, the extent of spread (staging), and response to therapy.

  • Hodgkin disease. In Hodgkin lymphoma, cells in the lymphatic system grow abnormally. They may spread beyond the lymphatic system. As the disease progresses, it inhibits your body's ability to fight infection. Hodgkin disease is relatively rare. Symptoms include:
    • Painless swelling of the lymph nodes in the neck, armpits or groin
    • Fatigue
    • Unexplained itching over the entire body
    • Fever with chills
    • Loss of appetite
  • Non-Hodgkin lymphoma. Non-Hodgkin lymphoma is cancer that develops in the lymphatic system from cells called lymphocytes. Common symptoms of non-Hodgkin lymphoma include:
    • Swollen lymph nodes
    • Fatigue
    • Fever

It is very important that you see your physician as soon as possible after developing symptoms. Treatment can be particularly effective when the disease is diagnosed early. 

We are one of the nation’s leaders in helping patients meet the challenges of cancer. An important part of your care plan at Indiana University Health is building your trust. Our patient- and family-centered approach ensures that you and family members are a part of your care team.

We treat lymphoma at all stages while caring for you as a whole person. We have extensive experience diagnosing and treating lymphoma and other blood cancers. Our experts are also involved in research that gives us a high level of expertise in advanced treatment of lymphoma. We are part of groundbreaking research on new therapies that include:

  • Molecularly targeted therapy. This research addresses the underlying reasons why some white blood cells become cancerous. We are also researching medications that attack cancerous cells but not normal cells.
  • Immune therapy. We are developing drugs that stimulate the immune system to attack cancerous cells on its own.

We see a large number of people with lymphoma each year, which gives us extensive experience with this disease. 

How We Can Help

How We Can Help

Lymphoma Treatment Information

Sometimes no immediate action is necessary to treat lymphoma, and we may recommend a watch-and-wait approach. However, depending on the stage of your cancer and other factors, we may begin treatment immediately. Treatments at IU Health include:

Lymphoma Locations & Physicians

Use the search options below to find treatments available in your area. 

Find a Specialist

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Lymphoma Support Services

Becoming familiar with the facts about lymphoma can help you work with us to defeat this disease. The websites below provide reliable information about lymphoma. Some also offer other resources to help you and your family manage the challenges that come with a serious illness.