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Paget’s Disease

Paget’s disease is a condition in which the body replaces normal bone tissue with enlarged, misshapen bones that are relatively fragile. It can affect one or several bones, but not the entire skeleton. The spine, skull, pelvis and leg are common sites of Paget’s disease. The condition occurs most often in people over age 50, and it affects more men than women.

Many people with Paget’s disease have no symptoms, or only mild ones. Possible symptoms include:

  • Pain in the bones or joints
  • Visible deformities such as bowing of the legs
  • Enlargement of the skull
  • Headache
  • Warm skin over affected bone

Potential complications of Paget’s disease include fractures, arthritis and hearing loss. We typically diagnose the condition using imaging techniques and blood tests.

It is not known what causes Paget’s disease. Some evidence suggests that it begins with a viral infection, but genetic factors may also play a role.

There is no cure for Paget’s disease, but it is a treatable condition. At Indiana University Health, our experienced specialists provide comprehensive diagnosis and treatment of Paget’s disease. Our goal is to help you reduce the rate at which your body replaces its bone cells, relieve symptoms and avoid complications so that you can lead an active, satisfying lifestyle.

Through our affiliation with Indiana University School of Medicine, we maintain access to the most innovative options for diagnosing and treating metabolic disorders of the bone such as Paget’s disease.

How We Can Help

How We Can Help

Paget’s Disease Treatment Information

Treatment for Paget’s disease is most effective when it begins early, before you develop complications such as arthritis or hearing loss. Our goals in treating Paget’s disease are to help you slow or halt bone deformation, control symptoms and avoid long-term problems that can interfere with your quality of life.

Treatment options for Paget’s disease include:

You are a vital member of your healthcare team at IU Health. We provide a precise evaluation of your condition based on our extensive clinical experience and advanced diagnostic technology. We then develop an individualized care plan that addresses your specific symptoms and concerns.


Paget’s Disease Locations & Physicians

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Paget’s Disease Support Services

The more you know about Paget’s disease, the better prepared you will be to manage it. Learn more at these websites: