- Methodist Research Institute
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The Neuroscience Research Laboratory investigates mechanisms in the regulation of growth, immune and inflammatory responses relevant to multiple sclerosis (MS), cancer and stem cells of the brain. We use molecular biology and bioinformatics tools to discover novel inflammatory signatures of MS for drug targeting.
We generate stem cell-derived brain cells and test their use in transplantation therapy for brain diseases. We study the nature of tumor stem cells and their significance to the development of brain cancer. We use novel nuclear receptors and nutraceuticals to regulate immune and stem cells for the treatment of MS, cancer and inflammatory diseases of the brain. We use relevant knockout and transgenic mice to study inflammation and cancer in the brain.