1903

  • Indiana University School of Medicine is founded

1921

  • The Riley Memorial Association, now the Riley Children's Foundations, is founded with the goal of building a children's hospital in memory of Hoosier Poet James Whitcomb Riley

1924

  • Riley Hospital for Children at IU Health opens

1935

  • President Franklin Delano Roosevelt attends the dedication of the hydrotheraputic pool for children with polio

1950

  • The Riley Research Building opens as an addition to the Riley Hospital for Children at IU Health campus

1951

  • Indiana's first pediatric cardiac catheterization laboratory opens at Riley at IU Health

1956

  • Indiana's first pediatric open heart procedure is performed at Riley at IU Health

1962

  • Riley at IU Health becomes the first hospital in the nation to perform percutaneous cardiac catheterization (a minimally invasive diagnostic and treatment procedure) in children

1966

  • Riley Hospital for Children at IU Health becomes the first hospital in Indiana, and one of the first in the nation, to utilize echocardiography to diagnose congenital heart defects

1971

  • Indiana's first and only pediatric burn center opens at Riley at IU Health
  • Indiana's first neonatal intensive care unit opens at Riley
  • The Parent Care Unit opens at Riley Hospital for Children at IU Health with open visitation, participation and in-room sleeping accommodations for parents, creating a national model for family-centered care

1975

  • The first staged Fontan procedure in Indiana is performed at Riley at IU Health. The surgery keeps oxygenated blood and deoxygenated blood from mixing in the heart

1980

  • Riley at IU Health becomes the first hospital in Indiana to provide outpatient surgical care for children

1983

  • Indiana's first pediatric cochlear implant procedure (to correct deafness) is performed at Riley at IU Health

1986

  • Indiana's first ECMO procedure (a form of heart-lung bypass for critically ill infants and children) is performed at Riley at IU Health

1988

  • Indiana's first pediatric liver transplant is performed at Riley at IU Health

1989

  • Indiana's first infant and newborn heart transplants are performed at Riley at IU Health

1991

  • The Herman B Wells Center for Pediatric Research opens at Riley Hospital for Children at IU Health

1994

  • Indiana's first and only pediatric cancer center, including the state's only stem cell transplant unit, opens at Riley at IU Health
  • Indiana's first pediatric cord blood transplant is performed at Riley at IU Health

1997

  • Riley Hospital for Children at IU Health joins IU Health University Hospital and IU Health Methodist Hospital to form IU Health Partners

1997-2006

  • IU Health Partners is listed among the nation's best hospitals by US News and World Report magazine for nine consecutive years

2000

  • The Riley at IU Health Outpatient Center opens as the nation's largest ambulatory care center for children

2001

  • The Riley at IU Health Sleep Disorders Center opens as the largest pediatric sleep lab in the world

2002

  • Indiana's only dedicated unit for children with heart defects, the Riley at IU Health Heart Center, opens
  • Riley at IU Health is one of just 19 hospitals in the country selected to perform Phase I pediatric cancer research protocols
  • One of the nation's three largest autism centers, the Christian Sarkine Autism Treatment Center, opens at Riley at IU Health

2003

  • First intestinal and multi-organ transplants in Indiana performed at Riley at IU Health
  • First hospital in the Eastern United States and only one of two in the U.S. to receive special government permission to use and implant the Berlin Heart, a ventricular assist device. The Berlin Heart is a new way to treat complex cardiac problems
  • First time Riley at IU Health surgeons use Repiphysis, a prosthetic implanted in an arm or leg
  • First hospital in Indiana to perform a pulmonary autograft mitral valve replacement, a revolutionary procedure to replace the mitral valve

2004

  • Family as Faculty program, part of the Family-Centered Care Program, launched at Riley Hospital for Children at IU Health
  • Riley at IU Health formalizes partnership with Deaconess Hospital in Evansville
  • Riley at IU Health celebrates 80th birthday
  • Riley at IU Health ranked as one of America's best children's hospitals according to Child Magazine
  • Riley at IU Health launches Riley Connections - A Telemedicine Program, allowing Riley physicians to consult with out-of-town physicians and patients

2005

  • Riley at IU Health announces its $500 million, 10-year plan
  • Riley Hospital for Children at IU Health North Medical Center opens
  • Phase V patient tower work begins
  • Riley at IU Health NICU is recognized as among the best five in the nation, according to Child magazine

2006

  • Child magazine ranked Riley Hospital for Children at IU Health 11th in the nation overall out of nearly 250 children's hospitals. The magazine also ranked the hospital's neonatal and pulmonary departments in the top 10.
  • The Riley Children's Foundation receives a $10 million gift from the Eli Lilly and Company Foundation to establish a world-class pediatric diabetes treatment and research program
  • Riley at IU Health is the first hospital in Indiana, and among a few hospitals in the nation, to use the Vertical Expandable Prosthetic Titanium Rib
  • Riley at IU Health's ECMO program ranked in the top five internationally

2007

  • The Simon Family announces a gift of $40 million toward the completion of the new 10-story, 675,000-square foot inpatient tower
  • Riley at IU Health places fourth among the nation's free¬standing children's hospitals with total research funding of $51 million, including $26.2 million from the National Institutes of Health
  • Riley at IU Health earns Level I Trauma verification making it one of 12 children's hospitals in the nation with this designation
  • IU Health joins with the IU Research and Technology Corporation in ownership of the Midwest Proton Radiotherapy Institute (now the IU Health Proton Therapy Center). One of just a few such centers in the country and the first one in the Midwest.
  • U.S.News & World Report's 2008 edition of America's Best Children's Hospitals ranked five specialty programs at Riley at IU Health among the top 30 children's hospitals in the nation
  • Riley at IU Health, Indiana University School of Medicine and Moi University School of Medicine completes construction on the new Riley Mother and Baby Hospital in Eldoret, Kenya
  • Riley at IU Health clinical and translational research a major component of the $25 million NIH Clinical and Translational Science Award to Indiana University School of Medicine
  • Riley at IU Health formalizes longtime relationship with the Capital Institute of Pediatrics of Beijing, China by becoming international sister hospitals

2009

  • Riley at IU Health ranked as one of America's best children's hospitals, according to Parents magazine
  • U.S.News & World Report's 2009–2010 edition of America's Best Children's Hospitals ranked seven specialty programs at Riley at IU Health among the top 30 children's hospitals in the nation
  • Riley at IU Health and the IU School of Medicine, Department of Pediatrics placed in the top 10 nationally in NIH funding ($18 million) with total extramural support at a historic high ($47 million) 

2011

  • Riley Hospital for Children at Indiana University Health ranked in 10 out of 10 specialties by U.S.News & World Report's Best Children's Hospitals.

2012

  • Riley Hospital for Children at Indiana University Health ranked in 10 out of 10 specialties by U.S.News & World Report's Best Children's Hospitals.

2013

  • Riley Hospital for Children at Indiana University Health ranked in 10 out of 10 specialties by U.S.News & World Report's Best Children's Hospitals.

2014

  • Riley Hospital for Children at Indiana University Health ranked in 9 pediatric specialties by U.S.News & World Report's Best Children's Hospitals.