Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: William Goggins, MD
Some patients needing kidney transplants have to wait much longer than others because of their sensitization to human leukocyte antigen (HLA). How are new desensitization protocols opening the door to transplantation for these patients who were previously ineligible? Discussing new approaches in desensitization therapy is Dr. William Goggins, kidney transplant surgical director at Indiana University Health.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Dr. Mary A. Maluccio
Treatment options for hepatocellular carcinoma include resection, ablation and transplantation. Which patients might benefit most from liver transplant? Dr. Mary Maluccio, director of the liver oncology program at Indiana University Health, discusses tumor characteristics that might indicate the best type of treatment for a patient's hepatocellular carcinoma. Hosted by Dr. Aaron Carroll.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Thomas Wozniak, MD
Currently, 3 to 5 million people per year suffer from heart failure in the United States; of which one-third suffers from Class III or Class IV heart failure. These patients are considered advanced heart failure, or end-stage heart disease. Host Dr. Aarron Carroll welcomes Dr. Thomas Wozniak, Surgical Director of the Indiana University Health Thoracic Transplant Program. Dr. Thomas discusses the advanced heart failure patient and the timing considerations for ventricular assist device (VADs) therapy and cardiac transplantation.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Patricia Scott, PhD
Transplantation offers patients a new opportunity for life, but the process of waiting and recovering after a transplant can be stressful. Host Dr. Aaron Carroll is joined by Patricia Scott, PhD as she discusses the biggest challenges that patients encounter before and after transplantation. Dr. Scott also touches on how health care providers can ensure a better quality of life and foster satisfying lifestyle for patients surrounding transplantation. Download, or play, the podcast to listen to their discussion!
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Rodrigo M. Vianna, MD
When might transplantation be indicated for patients with slow growing abdominal tumors, such as nueroendocrine and desmoids tumor? How common are multivisceral transplants? What are advantages and disadvantages of multivisceral transplantation? Host Dr. Aaron Caroll welcomes Dr. Rodrigo Vianna, Intestinal Transplant Surgical Director at Indiana University Health, Indianapolis, Indiana. Dr. Vianna answers these important questions and much more. Download, or hit play, to listen to this conversation.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Audrey A. Krause, PhD
There are psychosocial issues that arise before, during and after organ transplantation. To address these issues comprehensively and proactively, many transplant centers are incorporating a psychological assessment as part of their protocol in evaluating patients being considered for transplantation. What are the psychological criteria for inclusion or exclusion for listing? And how are psychosocial issues managed for patients both before and after surgery? Host Dr. Aaron Carroll is joined by Dr. Audrey Krause, Assistant professor of clinical psychology at the Indiana University School of Medicine, who will address these questions and more.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: John M Reynolds, MD
Which patients are good candidates for lung transplantation? How sick does a patient need to be to qualify? How does the transplant allocation system work? Host Aaron Caroll, MD welcomes John M. Reynolds, MD, Medical Director of Indiana University Health Lung Transplant Program, as he discusses these questions and other considerations regarding potential lung transplant candidates, including the lung allocation score system, and how to assess the optimal time frame to transplant patients to best improve overall quality of life.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Paul Kwo, MD
Approximately three million people in the US have hepatitis C. In some cases, hepatitis C can be completely cured. However, many with the condition may be asymptomatic for decades and thus are not diagnosed until the disease has progressed into later stages. This is problematic, because when hepatitis C advances, it may cause scarring of the liver. When should liver transplant be considered for these patients? And what is the rate of recurrence and necessity for re-transplantation? Dr. Paul Kwo, medical director of the adult liver transplant program at Indiana University Health, discusses treatment options for patients with various stages of hepatitis C, as well as the evaluation process for those with advanced hepatitis C who are liver transplant candidates. Dr. Aaron Carroll hosts.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Jonathan Fridell, MD
Although most patients with type 1 diabetes are able to rely on insulin to effectively manage their condition, sometimes insulin is not enough. When should these patients consider pancreas and/or kidney transplant? Dr. Jonathan Fridell, surgical director of the pancreas transplant program at Indiana University Health, talks with host Dr. Aaron Carroll about the benefits of separate or simultaneous pancreas and kidney transplantation, and says that such transplants can effectively cure patients of their type 1 diabetes. Of course, not every patient with type 1 diabetes is an appropriate candidate for transplant, and sometimes the side effects of immunosuppresive drugs are serious. What are the factors that influence a patient's eligibility for pancreas and kidney transplant? If a patient already has a kidney transplant, are there any disadvantages to getting a pancreas transplant, since these patients are already on immunosuppressive medications?
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Drs. Paul Helft, MD and Joseph Tector, MD, PhD
The necessity for transplantation of living cells from other species, or xenotransplantation, may arise when human donors are not available, a bridge organ is needed, or animal cells can provide a unique benefit to patients. Host Dr. Aaron Carroll's guests are xenotransplantation experts Dr. Paul Helft, director of the Charles Warren Fairbanks Center for Medical Ethics at Indiana University Health, and Dr. Joseph Tector, chief of transplant surgery at Indiana University School of Medicine. What is the history of xenotransplantation? What donor species are currently the subject of the most promising research in terms of solid organ transplantation and overcoming immunologic barriers and infection? Find out which patients might be the first to benefit.
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Paul R. Helft, MD, A. Joseph Tector, MD, PhD
One of the most pressing problems in transplant medicine is the shortage of available organ donors to keep up with high demand. What are the ethical considerations of solving the liver shortage problem with xenotransplantation? Host Dr. Aaron Carroll welcomes Drs. Tector and Helft for the second part in a discussion of xenotransplantation. Dr. Joseph Tector directs the section of transplant surgery's xenotransplantation research program at the Indiana University School of Medicine. Dr. Paul Helft is director of the Charles Warren Fairbanks Center for Medical Ethics at Indiana University Health, and is a member of the IU Health Ethics Committee and co-chair of the IU Health Ethics Consultation Subcommittee.
Organ Shortages, and When Living Organ Donation Might be a Viable Alternative to Deceased Organ Donation
Original Air Date: 09/21/2012 | Hosted by: Dr. Aaron Carroll | Guest: Dr. Tim Taber
Patients needing transplantation have two options--receiving an organ from a deceased donor or a living donor. In which cases might living organ donation be a viable option, and what are the advantages to this procedure? Dr. Tim Taber, medical director of the kidney and pancreas transplant program at Indiana University Health, discusses the issue of organ shortages, how organs are allocated and the process of living organ donation. Dr. Aaron Carroll hosts.