Indiana University Health Arnett Hospital Cancer Center gives north central Indiana residents a leading choice in comprehensive cancer care and treatment. IU Health Arnett Hospital Cancer Center provides new technologies, clinical expertise, clinical research options and a multidisciplinary approach to care. We also offer you patient-centered cancer care. That means you are able to address your individual goals, values and condition. Your care team will acknowledge those goals and preferences in creating a personalized treatment plan for you.

At IU Health Arnett Hospital Cancer Center, our board certified physicians treat a wide spectrum of cancers. We strive to bring the newest and most innovative treatments to the region. Because your needs will change throughout cancer treatment, we provide convenient, expert services and resources to meet them.

Our highly skilled cancer specialists, including primary care physicians, medical oncologists, radiation oncologists, surgeons, dietitians, physical therapists, chaplains, social workers and pharmacists work with you to develop an effective treatment plan personalized for your needs. Your treatment may include options such as surgery, chemotherapy, radiation therapy or even clinical trials.

As part of Indiana’s largest cancer care network, IU Health Arnett Hospital Cancer Center partners with the Indiana University School of Medicine and the Indiana University Health Melvin & Bren Simon Cancer Center, the state’s only cancer center with National Cancer Institute designation. These partnerships give our patients access to leading-edge treatments and innovative cancer research.

IU Health Arnett Hospital Cancer Center participates in a variety of clinical trials, which use new ideas and techniques to treat cancer. Many cancers, such as breast cancer, lymphoma, ovarian cancer and lung cancer, are treated using clinical trials. Clinical trials may include the use of new chemotherapy drugs, different radiation therapies or immunotherapy. Not all patients qualify for clinical trials. If you are interested in participating in a clinical trial, you should speak to your physician.

Medical Oncology

Medical oncology is a specialty of internal medicine that deals with the diagnosis and treatment of cancer. Medical oncologists at IU Health Arnett Cancer Center provide advanced therapies that are customized to treat each patient’s cancer. Both IU Health Arnett Hospital Cancer Center locations maintain on-site chemotherapy pharmacies, staffed by pharmacists.


Chemotherapy uses drugs that are given intravenously through an injection or by mouth. These drugs destroy cancer cells by slowing their growth and reproduction. Physicians may recommend chemotherapy alone or combine it with radiation therapy or surgery. Side effects of chemotherapy can include nausea, vomiting, hair loss and mouth sores. IU Health Arnett Hospital Cancer Center use new and effective approaches in an effort to prevent or moderate these side effects and make treatment as painless as possible.

Biological Therapy

Biological therapy, or immunotherapy, uses compounds or derivatives found in the body to fight malignancy. The aim of this therapy is to enhance your immune system so it can destroy cancer cells. Two popular biological therapies are Interferons and Interleukin-2. Interferon mimics your body’s cellular proteins and Interleukin-2 stimulates and enhances the function of other T-cells, which are immune cells that help destroy disease. Together, these two biological therapies help destroy cancerous tumors.

Clinical Trials

Clinical trials are vital in the fight against cancer because they answer important questions about which drug therapy, or combination of therapies, is the most effective for a particular type of cancer. IU Health Arnett Hospital Cancer Center participates in clinical trials for Phase I-IV cancers. Your oncologist can explain more about clinical trials and if participation is appropriate for your situation.

Radiation Oncology

Skilled radiation oncologists at IU Health Arnett Hospital Cancer Center use a number of radiation technologies to treat cancer. Each treatment can be personalized to your needs with the goal of minimizing the radiation necessary to destroy cancerous cells.

Radiation treatment may be used in early-stage cancers to destroy cancer. It can be used before surgery to shrink a tumor or after surgery to prevent cancer from returning. Radiation may also be used to treat pain caused by cancer. It may be used alone or combined with other treatments, such as chemotherapy and surgery. The radiation oncology team uses advanced radiation techniques to deliver higher radiation doses to cancer cells while limiting doses to healthy tissue.

Intensity Modulated Radiation Therapy (IMRT)

Intensity modulated radiation therapy (IMRT) employs a powerful, advanced computer program to plan a precise dose of radiation in three dimensions, based on individual tumor size, shape and location. IMRT directs radiation at the tumor and precisely modulates the intensity of extremely thin beams of radiation. IMRT delivers new accuracy to treatment of difficult-to-reach tumors, such as tumors in the head, neck, prostate, lung, pancreas and brain. IMRT is useful for patients who have already had conventional radiation therapy and whose tumors have come back.

High-Dose Rate (HDR) Brachytherapy

High-dose rate (HDR) brachytherapy delivers radiation directly to tumors and, in many cases, is an effective alternative to conventional surgery. HDR is usually administered over only a few days with very little discomfort to the patient. For many patients with breast cancer, HDR can treat early-stage breast cancers, eliminating the need for six weeks of conventional whole-breast treatment. Less radiation reaches the lungs and heart compared to the amount released during traditional external beam radiation treatments. HDR is an effective alternative to surgical treatment of prostate cancer and offers a survival rate similar to radical prostatectomy, which removes the prostate.

MammoSite Radiation Therapy System (RTS)

The MammoSite device is a balloon catheter that is inserted into a cavity created by a lumpectomy—the surgical removal of a breast tumor. MammoSite radiation therapy system (RTS) delivers radiation from inside the lumpectomy cavity over a four- to five-day period. The device targets radiation to the area where tumors are most likely to recur and minimizes exposure to healthy tissue.

External Beam Radiation Therapy

External beam radiation therapy uses a machine to deliver radiation to a specific, focused area on the body. Radiation oncologists can use 2D or 3D planning to aim the radiation at cancerous cells. The therapy can be precisely aimed and custom shaped to affect as few healthy cells as possible. It is delivered through dual-energy photon beams, non-coplanar beams or multiple electron beams.

Permanent Seeds Implant

For patients with prostate cancer, permanent seed implants provide highly-targeted therapy. During a one- to two-hour procedure, radioactive seeds are permanently implanted into the prostate. These seeds allow high doses of radiation to be delivered with minimal harm to surrounding tissue. After about 10 months, the seeds no longer release radiation.

Surgical Oncology

Surgery is one of the oldest forms of cancer treatments and offers the greatest chance for diagnosis and cure for many types of cancer. Advances in surgical techniques and equipment have allowed surgeons to successfully operate on a growing number of cancer patients than ever before. Most people with cancer will have some type of surgical procedure to prevent, detect, stage, cure, debulk, provide pain relief, support other treatments or reconstruct tissues.

Sentinel Node Biopsy

Sentinel node biopsy is used to determine whether cancer has spread beyond the primary site to the closest lymph node. The minimally invasive procedure may prevent the more extensive surgery of removing all lymph nodes.

Head and Neck Surgery

Surgical management for head and neck cancer requires extensive knowledge of cancer's origin, behavior and responses to therapy. These procedures are very intricate. Surgery is a treatment option when used in the early stages of the disease and allows for relatively fast recovery. Surgery is often followed by radiation. When all other therapies fail, surgery can also lead to improved quality of life for advanced cancers.


Cryosurgery (also called cryotherapy) uses extreme cold to destroy cancer cells. For internal tumors, liquid nitrogen is circulated through an instrument called a cryoprobe, or needle, which is placed in contact with the tumor. Surgeons use ultrasound to guide the cryoprobe, monitor the freezing of cells and spare nearby healthy tissue. Cryosurgery is traditionally used to treat early-stage skin cancers.


Lumpectomy removes breast cancer through a very small incision to conserve the breast. If a large amount of breast tissue is removed, plastic surgery may reshape the breast to its natural appearance.


Mastectomy removes the breast, with or without preservation of the skin and nipple. Advanced forms of mastectomy allow reconstruction surgery for a natural appearance.

Cancer Screenings

Early detection is important in the success of cancer treatment. Finding cancer before it is advanced leads to better outcomes, and sometimes, less invasive treatments. The American Cancer Society has guidelines for when screenings should occur. Follow these guidelines or talk to your physician about starting earlier if you have a family history that puts you at a higher risk for certain cancers.

At IU Health Arnett Hospital, we offer screenings for breast cancer, cervical cancer, colon cancer, lung cancer, prostate cancer and skin cancer.

Precision Genomics

The IU Health Arnett Cancer Center Precision Genomics program allows our cancer experts to tailor treatment plans based on each patient’s unique cancer. Patients can be referred to the program by their medical oncologist. The program includes genomic consultation, cancer diagnostic genomic testing and patient education. To learn more about precision genomics at IU Health Cancer Centers, please visit

Additional Contact Information

For Patients
If you would like to participate or get more information about clinical trials, please call 765.448.7599.

View the IU Health Arnett Cancer Center Annual Report and Screening Outcomes.