Leukemia

​Overview

The most common forms of leukemia fall into two major categories:

• Acute leukemia. With acute forms of leukemia, abnormal white blood cells do not fight disease. As leukemia cells collect in the blood, normal white blood cells cannot do their work and the body becomes susceptible to infections it normally fights off. This type of leukemia usually develops quickly.
• Chronic leukemia. Chronic leukemia involves an increase of abnormal white blood cells that accumulate in the blood and crowd out normal blood cells. These leukemia cells usually develop slowly.

Acute leukemia usually causes more severe symptoms that may require extensive treatment. Chronic leukemia can sometimes cause few symptoms, and it is possible to have this disease and not know it.

Symptoms of leukemia may include:

• Swollen lymph nodes (especially lymph nodes in the neck or armpit)
• Fevers or night sweats
• Frequent infections
• Weakness or fatigue
• Bleeding and bruising easily
• Pain in the bones or joints
• Swelling or discomfort in the abdomen
• Unexplained weight loss or loss of appetite

Treatment

At IU Health, cancer experts make it their goal to heal you, not just treat your cancer.

Your highly-skilled team uses a wide spectrum of treatments for leukemia. The particular treatments you receive depend on the personalized treatment plan your physicians develop with you and your family. They take into account your special needs and preferences, so the treatment you receive does its job effectively.

Treatments for leukemia include:

Chemotherapy

Strong chemotherapy medicines destroy leukemia cells. You may receive chemotherapy in a clinic, at your physician’s office or at home. Some people need to stay in the hospital during treatment. With advances in chemotherapy, as many as 80 percent of people undergoing this treatment continue to live normal lives.

Targeted therapy

This relatively new class of drugs blocks the growth and spread of cancer cells. They tend to treat leukemia effectively, often with milder side effects than traditional chemotherapy.

Radiation

Radiation can destroy leukemia cells in certain parts of the body. While lying on a treatment table, a large device directs high-energy rays at your body to kill the cancer cells. You may receive radiation therapy in combination with chemotherapy. You typically receive radiation therapy at the hospital or a clinic.

Bone marrow transplant

Bone marrow transplant, also known as stem cell transplant, is when healthy blood stem cells are placed into your body to grow new bone marrow and blood cells when your marrow has been damaged by chemotherapy or disease.

Chimeric Antigen Receptor (CAR) T-Cell Therapy

CAR T-cell therapy is an emerging form of cancer immunotherapy. IU Health is the only healthcare system in Indiana to offer CAR T-cell therapy to treat non-Hodgkin lymphoma and Acute Lymphoblastic Leukemia (ALL).