CAR T-Cell Therapy

Groundbreaking gene therapy cancer treatment for non-Hodgkin's lymphoma and acute lymphoblastic leukemia

Chimeric Antigen Receptor (CAR) T-cell therapy is an emerging form of cancer immunotherapy.

IU Health is the only healthcare system in Indiana to offer CAR T-cell therapy to treat non-Hodgkin’s lymphoma and acute lymphoblastic leukemia.

CAR-T cell therapy is an emerging form of cancer immunotherapy. IU Health is the only healthcare system in Indiana to offer CAR-T cell therapy to treat non-Hodgkin lymphoma.

What is CAR T-Cell Therapy?

This CAR T-cell therapy involves supercharging a patient’s T cells to recognize and attack cancer cells.

Your T cells are a kind of white blood cell that has the job of targeting and destroying bacteria, viruses, and cancer cells.

However, with certain types of immune system cell cancers, your T cells may not be able to do their job properly. That’s where CAR T-cell therapy may help. It is used after failure of two other kinds of treatment.

Treatment

For this treatment, your blood will be collected over the course of a few hours and passed through a machine that separates out some of your T-cells.

After your T cells are collected, they will be sent to a laboratory and modified to become CAR T cells. You will undergo three days of low-dose conditioning chemotherapy to prepare your body for treatment. Your CAR T cells will then be infused back into your body to help recognize and attack your cancer cells.

What to Expect with CAR T-Cell Therapy

What is CAR T-Cell Therapy?

This CAR T-cell therapy involves supercharging a patient’s T cells to recognize and attack cancer cells.

Your T cells are a kind of white blood cell that has the job of targeting and destroying bacteria, viruses, and cancer cells.

However, with certain types of immune system cell cancers, your T cells may not be able to do their job properly. That’s where CAR T-cell therapy may help. It is used after failure of two other kinds of treatment.

Treatment

For this treatment, your blood will be collected over the course of a few hours and passed through a machine that separates out some of your T-cells.

After your T cells are collected, they will be sent to a laboratory and modified to become CAR T cells. You will undergo three days of low-dose conditioning chemotherapy to prepare your body for treatment. Your CAR T cells will then be infused back into your body to help recognize and attack your cancer cells.

  • Am I a candidate for CAR T-cell therapy?
  • What are some side effects of CAR T-cell therapy?
  • Can my cancer be treated by CAR T-cell therapy?
  • When is CAR T-cell therapy used in treatment?

Questions to Ask Your Provider About CAR T-Cell Therapy

  • Am I a candidate for CAR T-cell therapy?
  • What are some side effects of CAR T-cell therapy?
  • Can my cancer be treated by CAR T-cell therapy?
  • When is CAR T-cell therapy used in treatment?

Patient Stories for CAR T-Cell Therapy