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IU Health Precision Genomics Program

Leading-edge science meets the art of interpretation

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Precision Genomics is currently available for patients with metastatic cancer with a solid tumor. We recommend that patients are referred into the program as soon as they present with metastatic disease even if other standards of care are being pursued. If you have a patient that would benefit from Precision Genomics, call the number below for questions or referrals.

Refer a Patient

Precision Genomics is currently available for patients with metastatic cancer with a solid tumor. We recommend that patients are referred into the program as soon as they present with metastatic disease even if other standards of care are being pursued. If you have a patient that would benefit from Precision Genomics, call the number below for questions or referrals.

You want to do everything you can to ensure that your patients with late-stage cancer are provided with the most sophisticated treatment options available. Please consider the Indiana University Health Precision Genomics program as a way to discover more options in your treatment strategy. This program gives you and your patients access to university-based expertise and the most leading-edge science in genomics.

Who's Eligible?

  • Adults with a solid tumor that has metastasized may be referred by their provider. We recommend that patients are referred into the program as soon as they present with metastatic disease even if other standards of care are being pursued.
  • Riley Children’s Health offers a pediatric program.

What Personalized Medicine Means for You

Watch: Cancer Care on an Individual Basis

Cancer treatment is no longer what it was just a few short years ago. Treatments continue to evolve and survival rates continue to improve. Precision genomics is the very definition of personalized medicine as it looks at the unique structure of your cancer.

The program at IU Health is one of the best in nation with specialized university-based expertise and the most leading-edge science in genomics. You have access to these specialized resources, testing, clinical trials, new drugs and education.

Overview

You want to do everything you can to ensure that your patients with late-stage cancer are provided with the most sophisticated treatment options available. Please consider the Indiana University Health Precision Genomics program as a way to discover more options in your treatment strategy. This program gives you and your patients access to university-based expertise and the most leading-edge science in genomics.

Who's Eligible?

  • Adults with a solid tumor that has metastasized may be referred by their provider. We recommend that patients are referred into the program as soon as they present with metastatic disease even if other standards of care are being pursued.
  • Riley Children’s Health offers a pediatric program.

What Personalized Medicine Means for You

Watch: Cancer Care on an Individual Basis

Cancer treatment is no longer what it was just a few short years ago. Treatments continue to evolve and survival rates continue to improve. Precision genomics is the very definition of personalized medicine as it looks at the unique structure of your cancer.

The program at IU Health is one of the best in nation with specialized university-based expertise and the most leading-edge science in genomics. You have access to these specialized resources, testing, clinical trials, new drugs and education.

The IU Health Precision Genomics program is changing cancer care by partnering with you.

  • Your patient remains your patient, and together you will decide which recommendations to pursue and when
  • Your patients can remain close to home with our convenient locations across central Indiana
  • You and your patient get access to the most leading-edge science in genomic testing
  • You and your patient get access to highly specialized experts where science meets the art of interpretation – this includes multidisciplinary clinical conference review, personalized recommendations and education
  • You and your patient can receive assistance with pursuing approval for genomic-directed therapy recommendations, if needed

What to Expect

Our program has been able to achieve results greater than many programs across the United States. We are dedicated to continue to increase the number of patients that are able to proceed to genomic-directed therapy.

Outcomes of Our Program

The top reasons patients did not go on genomic-directed therapy were:

  • Declining performance status of the patient
  • Clinical trial availability/lack of availability
  • Patient deciding they may pursue genomic-directed therapy in the future

Our Process

Our goal is to make this process as easy for you and your patient as possible. Once your patient is referred to the program, they will have two consultations with us. We will keep you informed of the process and you and your patient will decide when and whether to pursue the genomic-directed recommendations.

Precision Genomics at IU Health: Step by step

1. Review and refer. Talk with your patient about the Precision Genomics program and how it functions. If you and your patient would like to participate in this program, refer your patient to the nearest IU Health Precision Genomics location.

2. Initial patient consultation and testing. If your patient is eligible and accepted by the program, they will meet with a precision genomics team at an IU Health location.

During this appointment, they will:

  • Learn more about the program and be able to ask questions
  • Be examined by one of our medical oncologists
  • Have blood drawn
  • Have a biopsy

3. Genomic testing. Patients in our program will receive comprehensive testing of the cancer and may also receive germline DNA testing. This allows us to scan everything and have the most comprehensive view of the attributes of your patient's cancer.

4. Clinical Conference evaluation. This is where science meets the art of interpretation. The IU Health Precision Genomics Clinical Conference is comprised of more than 20 multidisciplinary IU Health and IU School of Medicine faculty and staff, including oncologists, genomics scientists, pathologists, pharmacists, nurses, and clinical trial specialists. This team will review the results of the genomic testing and will debate and discuss the best genomic-directed treatment options available to your patient.

5. Patient recommendation consultation. Once the recommendations have been made by the clinical conference, your patient will return to the nearby Precision Genomics program for a second consultation to review the findings and recommendations. At this time, we are able to answer any specific questions your patient may have about the recommendations. Your patient should expect to attend this recommendation consultation about 6- 8 weeks after their tissue has been submitted for testing.

6. Information sharing. You will receive the genomic report, clinical notes, and our recommendation electronically or via fax, so you are always fully informed to speak with your patient.

7. Path forward. Equipped with new, detailed information about your patient's tumor genetics, you and your patient will decide which recommendations to pursue and when.

What Can You Expect from the Genomic Recommendation?

Depending on the genomic analysis, past history and clinical conference recommendations, there are several options that may be recommended for your patients, including:

  • Pharmacological therapies approved by the FDA for other indications
  • Clinical trials of targeted therapies
  • Phase I or Phase II clinical trials at IU Health or other centers across the Midwest

Why IU Health for Precision Genomics

The IU Health Precision Genomics program is changing cancer care by partnering with you.

  • Your patient remains your patient, and together you will decide which recommendations to pursue and when
  • Your patients can remain close to home with our convenient locations across central Indiana
  • You and your patient get access to the most leading-edge science in genomic testing
  • You and your patient get access to highly specialized experts where science meets the art of interpretation – this includes multidisciplinary clinical conference review, personalized recommendations and education
  • You and your patient can receive assistance with pursuing approval for genomic-directed therapy recommendations, if needed

What to Expect

Our program has been able to achieve results greater than many programs across the United States. We are dedicated to continue to increase the number of patients that are able to proceed to genomic-directed therapy.

Outcomes of Our Program

The top reasons patients did not go on genomic-directed therapy were:

  • Declining performance status of the patient
  • Clinical trial availability/lack of availability
  • Patient deciding they may pursue genomic-directed therapy in the future

Our Process

Our goal is to make this process as easy for you and your patient as possible. Once your patient is referred to the program, they will have two consultations with us. We will keep you informed of the process and you and your patient will decide when and whether to pursue the genomic-directed recommendations.

Precision Genomics at IU Health: Step by step

1. Review and refer. Talk with your patient about the Precision Genomics program and how it functions. If you and your patient would like to participate in this program, refer your patient to the nearest IU Health Precision Genomics location.

2. Initial patient consultation and testing. If your patient is eligible and accepted by the program, they will meet with a precision genomics team at an IU Health location.

During this appointment, they will:

  • Learn more about the program and be able to ask questions
  • Be examined by one of our medical oncologists
  • Have blood drawn
  • Have a biopsy

3. Genomic testing. Patients in our program will receive comprehensive testing of the cancer and may also receive germline DNA testing. This allows us to scan everything and have the most comprehensive view of the attributes of your patient's cancer.

4. Clinical Conference evaluation. This is where science meets the art of interpretation. The IU Health Precision Genomics Clinical Conference is comprised of more than 20 multidisciplinary IU Health and IU School of Medicine faculty and staff, including oncologists, genomics scientists, pathologists, pharmacists, nurses, and clinical trial specialists. This team will review the results of the genomic testing and will debate and discuss the best genomic-directed treatment options available to your patient.

5. Patient recommendation consultation. Once the recommendations have been made by the clinical conference, your patient will return to the nearby Precision Genomics program for a second consultation to review the findings and recommendations. At this time, we are able to answer any specific questions your patient may have about the recommendations. Your patient should expect to attend this recommendation consultation about 6- 8 weeks after their tissue has been submitted for testing.

6. Information sharing. You will receive the genomic report, clinical notes, and our recommendation electronically or via fax, so you are always fully informed to speak with your patient.

7. Path forward. Equipped with new, detailed information about your patient's tumor genetics, you and your patient will decide which recommendations to pursue and when.

What Can You Expect from the Genomic Recommendation?

Depending on the genomic analysis, past history and clinical conference recommendations, there are several options that may be recommended for your patients, including:

  • Pharmacological therapies approved by the FDA for other indications
  • Clinical trials of targeted therapies
  • Phase I or Phase II clinical trials at IU Health or other centers across the Midwest

Our Highly Specialized Experts

In 2014, IU Health under the leadership of Dr. Milan Radovich and Dr. Bryan Schneider launched the Precision Genomics program. The goal of the program was and is to discover more options in a patient’s treatment strategy based on their genomic mutations. This program has sequenced over 2000 patients to date.

Clinical Conference: Where Science Meets Art of Interpretation

Your patient’s findings will be analyzed by more than 20 multi-disciplinary IU Health and Indiana University School of Medicine faculty and staff, including oncologists, genomics scientists, pathologists, pharmacy specialists, nurses and clinical trial specialists.

This comprehensive Precision Genomics Clinical Conference team will use the latest genomic tools to determine the best available treatment options for you, while minimizing the potential for adverse side effects. You are welcome to participate in the clinical conference review of your patient.

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Precision genomics and cancer treatment is evolving at a rapid pace and research is the key component to the evolution. In addition to our clinical precision genomics program, IU Health and Indiana University researchers are bringing promising discoveries to you as quickly as possible through clinical trials.

As part of the part of our program, our team will also look for clinical trials for which your patient may be a match. This extensive search extends beyond clinical trials offered by IU Health and Indiana University.

Research

Precision genomics and cancer treatment is evolving at a rapid pace and research is the key component to the evolution. In addition to our clinical precision genomics program, IU Health and Indiana University researchers are bringing promising discoveries to you as quickly as possible through clinical trials.

As part of the part of our program, our team will also look for clinical trials for which your patient may be a match. This extensive search extends beyond clinical trials offered by IU Health and Indiana University.

Are you a patient looking for Precision Genomics information?
Visit our page for patients.

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